Intermittent BRAF inhibition in advanced BRAF mutated melanoma results of a phase II randomized tria...
Intermittent BRAF inhibition in advanced BRAF mutated melanoma results of a phase II randomized trial
About this item
Full title
Author / Creator
Gonzalez-Cao, Maria , Mayo de las Casas, Clara , Oramas, Juana , Berciano-Guerrero, Miguel A. , de la Cruz, Luis , Cerezuela, Pablo , Arance, Ana , Muñoz-Couselo, Eva , Espinosa, Enrique , Puertolas, Teresa , Diaz Beveridge, Roberto , Ochenduszko, Sebastian , Villanueva, Maria-Jose , Basterretxea, Laura , Bellido, Lorena , Rodriguez, Delvys , Campos, Begoña , Montagut, Clara , Drozdowskyj, Ana , Molina, Miguel A. , Lopez-Martin, Jose Antonio and Berrocal, Alfonso
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Combination treatment with BRAF (BRAFi) plus MEK inhibitors (MEKi) has demonstrated survival benefit in patients with advanced melanoma harboring activating
BRAF
mutations. Previous preclinical studies suggested that an intermittent dosing of these drugs could delay the emergence of resistance. Contrary to expectations, the first published ph...
Alternative Titles
Full title
Intermittent BRAF inhibition in advanced BRAF mutated melanoma results of a phase II randomized trial
Authors, Artists and Contributors
Author / Creator
Mayo de las Casas, Clara
Oramas, Juana
Berciano-Guerrero, Miguel A.
de la Cruz, Luis
Cerezuela, Pablo
Arance, Ana
Muñoz-Couselo, Eva
Espinosa, Enrique
Puertolas, Teresa
Diaz Beveridge, Roberto
Ochenduszko, Sebastian
Villanueva, Maria-Jose
Basterretxea, Laura
Bellido, Lorena
Rodriguez, Delvys
Campos, Begoña
Montagut, Clara
Drozdowskyj, Ana
Molina, Miguel A.
Lopez-Martin, Jose Antonio
Berrocal, Alfonso
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_bcf9c314e06143fd83f1b0b564d0166e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bcf9c314e06143fd83f1b0b564d0166e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-26572-6
