Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells
Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Cancer therapy has traditionally focused on eliminating fast-growing populations of cells. Yet, an increasing body of evidence suggests that small subpopulations of cancer cells can evade strong selective drug pressure by entering a ‘persister’ state of negligible growth. This drug-tolerant state has been hypothesized to be part of an initial strat...
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Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells
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TN_cdi_doaj_primary_oai_doaj_org_article_bd1a3c50ad1a402d9bff233756a1c84e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bd1a3c50ad1a402d9bff233756a1c84e
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms10690
