NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart
NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart
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Author / Creator
Müller, Marion , Eghbalian, Rose , Boeckel, Jes-Niels , Frese, Karen S. , Haas, Jan , Kayvanpour, Elham , Sedaghat-Hamedani, Farbod , Lackner, Maximilian K. , Tugrul, Oguz F. , Ruppert, Thomas , Tappu, Rewati , Martins Bordalo, Diana , Kneuer, Jasmin M. , Piekarek, Annika , Herch, Sabine , Schudy, Sarah , Keller, Andreas , Grammes, Nadja , Bischof, Cornelius , Klinke, Anna , Cardoso-Moreira, Margarida , Kaessmann, Henrik , Katus, Hugo A. , Frey, Norbert , Steinmetz, Lars M. and Meder, Benjamin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
To adapt to changing hemodynamic demands, regulatory mechanisms modulate actin-myosin-kinetics by calcium-dependent and -independent mechanisms. We investigate the posttranslational modification of human essential myosin light chain (ELC) and identify NIMA-related kinase 9 (NEK9) to interact with ELC. NEK9 is highly expressed in the heart and the i...
Alternative Titles
Full title
NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart
Authors, Artists and Contributors
Author / Creator
Eghbalian, Rose
Boeckel, Jes-Niels
Frese, Karen S.
Haas, Jan
Kayvanpour, Elham
Sedaghat-Hamedani, Farbod
Lackner, Maximilian K.
Tugrul, Oguz F.
Ruppert, Thomas
Tappu, Rewati
Martins Bordalo, Diana
Kneuer, Jasmin M.
Piekarek, Annika
Herch, Sabine
Schudy, Sarah
Keller, Andreas
Grammes, Nadja
Bischof, Cornelius
Klinke, Anna
Cardoso-Moreira, Margarida
Kaessmann, Henrik
Katus, Hugo A.
Frey, Norbert
Steinmetz, Lars M.
Meder, Benjamin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_bdd3c98ae2ae446c8307d5af259ac8e7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bdd3c98ae2ae446c8307d5af259ac8e7
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-33658-2
