Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease i...
Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer
About this item
Full title
Author / Creator
Haderk, Franziska , Chou, Yu-Ting , Cech, Lauren , Fernández-Méndez, Celia , Yu, Johnny , Olivas, Victor , Meraz, Ismail M. , Barbosa Rabago, Dora , Kerr, D. Lucas , Gomez, Carlos , Allegakoen, David V. , Guan, Juan , Shah, Khyati N. , Herrington, Kari A. , Gbenedio, Oghenekevwe M. , Nanjo, Shigeki , Majidi, Mourad , Tamaki, Whitney , Pourmoghadam, Yashar K. , Rotow, Julia K. , McCoach, Caroline E. , Riess, Jonathan W. , Gutkind, J. Silvio , Tang, Tracy T. , Post, Leonard , Huang, Bo , Santisteban, Pilar , Goodarzi, Hani , Bandyopadhyay, Sourav , Kuo, Calvin J. , Roose, Jeroen P. , Wu, Wei , Blakely, Collin M. , Roth, Jack A. and Bivona, Trever G.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Targeted therapy is effective in many tumor types including lung cancer, the leading cause of cancer mortality. Paradigm defining examples are targeted therapies directed against non-small cell lung cancer (NSCLC) subtypes with oncogenic alterations in EGFR, ALK and KRAS. The success of targeted therapy is limited by drug-tolerant persister cells (...
Alternative Titles
Full title
Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer
Authors, Artists and Contributors
Author / Creator
Chou, Yu-Ting
Cech, Lauren
Fernández-Méndez, Celia
Yu, Johnny
Olivas, Victor
Meraz, Ismail M.
Barbosa Rabago, Dora
Kerr, D. Lucas
Gomez, Carlos
Allegakoen, David V.
Guan, Juan
Shah, Khyati N.
Herrington, Kari A.
Gbenedio, Oghenekevwe M.
Nanjo, Shigeki
Majidi, Mourad
Tamaki, Whitney
Pourmoghadam, Yashar K.
Rotow, Julia K.
McCoach, Caroline E.
Riess, Jonathan W.
Gutkind, J. Silvio
Tang, Tracy T.
Post, Leonard
Huang, Bo
Santisteban, Pilar
Goodarzi, Hani
Bandyopadhyay, Sourav
Kuo, Calvin J.
Roose, Jeroen P.
Wu, Wei
Blakely, Collin M.
Roth, Jack A.
Bivona, Trever G.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_be0a7eca3725431ab19bfe58739629b9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_be0a7eca3725431ab19bfe58739629b9
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-47423-0
