Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothia...
Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protease
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Publisher
England: Taylor & Francis
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Language
English
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England: Taylor & Francis
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Contents
The global outbreak of the COVID-19 pandemic provokes scientists to make a prompt development of new effective therapeutic interventions for the battle against SARS-CoV-2. A new series of N-(5-nitrothiazol-2-yl)-carboxamido derivatives were designed and synthesised based on the structural optimisation principle of the SARS-CoV Mpro co-crystallized...
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Full title
Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protease
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TN_cdi_doaj_primary_oai_doaj_org_article_be13a2cc18784d8c9feb702560387273
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_be13a2cc18784d8c9feb702560387273
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ISSN
1475-6366,1475-6374
E-ISSN
1475-6374
DOI
10.1080/14756366.2022.2105322
