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KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage

KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_be6a42f12a9c4b1cab7c97cc51dcab90

KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage

About this item

Full title

KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2020-06, Vol.9

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

The Krüppel-associated box zinc finger protein (KRAB-ZFP) family diversified in mammals. The majority of human KRAB-ZFPs bind transposable elements (TEs), however, since most TEs are inactive in humans it is unclear whether KRAB-ZFPs emerged to suppress TEs. We demonstrate that many recently emerged murine KRAB-ZFPs also bind to TEs, including the...

Alternative Titles

Full title

KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_be6a42f12a9c4b1cab7c97cc51dcab90

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_be6a42f12a9c4b1cab7c97cc51dcab90

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.56337

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