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Longitudinal analysis reveals age-related changes in the T cell receptor repertoire of human T cell...

Longitudinal analysis reveals age-related changes in the T cell receptor repertoire of human T cell...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_be9e3fbb629f4693b28c5ccd2679bf6e

Longitudinal analysis reveals age-related changes in the T cell receptor repertoire of human T cell subsets

About this item

Full title

Longitudinal analysis reveals age-related changes in the T cell receptor repertoire of human T cell subsets

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2022-09, Vol.132 (17), p.1-13

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

A diverse T cell receptor (TCR) repertoire is essential for protection against a variety of pathogens and T cell repertoire size is believed to decline with age. However, the precise size of human TCR repertoire in total and subsets of T cells, and their changes with age are not fully characterized. We conducted a longitudinal analysis of the human...

Alternative Titles

Full title

Longitudinal analysis reveals age-related changes in the T cell receptor repertoire of human T cell subsets

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_be9e3fbb629f4693b28c5ccd2679bf6e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_be9e3fbb629f4693b28c5ccd2679bf6e

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI158122

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