Marburg virus-like particles by co-expression of glycoprotein and matrix protein in insect cells ind...
Marburg virus-like particles by co-expression of glycoprotein and matrix protein in insect cells induces immune responses in mice
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Author / Creator
Gai, Weiwei , Zheng, Xuexing , Wang, Chong , Wang, Hualei , Zhao, Yongkun , Wang, Qi , Wong, Gary , Zhang, Weijiao , Feng, Na , Qiu, Boning , Chi, Hang , Li, Nan , Wang, Tiecheng , Gao, Yuwei , Shan, Junjie , Yang, Songtao and Xia, Xianzhu
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Marburg virus (MARV) causes severe haemorrhagic fever in humans and nonhuman primates and has a high mortality rate. However, effective drugs or licensed vaccines are not currently available to control the outbreak and spread of this disease.
In this study, we generated MARV virus-like particles (VLPs) by co-expressing the glycoprotein (GP) and...
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Full title
Marburg virus-like particles by co-expression of glycoprotein and matrix protein in insect cells induces immune responses in mice
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_beb3be5262164ba7bd020cad2f84c20b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_beb3be5262164ba7bd020cad2f84c20b
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ISSN
1743-422X
E-ISSN
1743-422X
DOI
10.1186/s12985-017-0869-3