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C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal tran...

C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal tran...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_beb8ddfc0b0b4b249f1fbb7841a7699b

C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal transition

About this item

Full title

C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal transition

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-02, Vol.11 (1), p.785-785, Article 785

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Extracellular signals such as TGF-β can induce epithelial-to-mesenchymal transition (EMT) in cancers of epithelial origin, promoting molecular and phenotypical changes resulting in pro-metastatic characteristics. We identified C/EBPα as one of the most TGF-β-mediated downregulated transcription factors in human mammary epithelial cells. C/EBPα expr...

Alternative Titles

Full title

C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal transition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_beb8ddfc0b0b4b249f1fbb7841a7699b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_beb8ddfc0b0b4b249f1fbb7841a7699b

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-14556-x

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