Molsidomine provides neuroprotection against vincristine-induced peripheral neurotoxicity through so...
Molsidomine provides neuroprotection against vincristine-induced peripheral neurotoxicity through soluble guanylyl cyclase activation
About this item
Full title
Author / Creator
Utkina-Sosunova, Irina , Chiorazzi, Alessia , de Planell-Saguer, Mariangels , Li, Hai , Meregalli, Cristina , Pozzi, Eleonora , Carozzi, Valentina Alda , Canta, Annalisa , Monza, Laura , Alberti, Paola , Fumagalli, Giulia , Karan, Charles , Moayedi, Yalda , Przedborski, Serge , Cavaletti, Guido and Lotti, Francesco
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Peripheral neurotoxicity is a dose-limiting adverse reaction of primary frontline chemotherapeutic agents, including vincristine. Neuropathy can be so disabling that patients drop out of potentially curative therapy, negatively impacting cancer prognosis. The hallmark of vincristine neurotoxicity is axonopathy, yet its underpinning mechanisms remai...
Alternative Titles
Full title
Molsidomine provides neuroprotection against vincristine-induced peripheral neurotoxicity through soluble guanylyl cyclase activation
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_becfb928778f4455b47dda2d76d7e062
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_becfb928778f4455b47dda2d76d7e062
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-70294-w
