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Cinnamides Target Leishmania amazonensis Arginase Selectively

Cinnamides Target Leishmania amazonensis Arginase Selectively

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_beefaca560cd4ecda25f10f910ca0fd9

Cinnamides Target Leishmania amazonensis Arginase Selectively

About this item

Full title

Cinnamides Target Leishmania amazonensis Arginase Selectively

Publisher

Switzerland: MDPI

Journal title

Molecules (Basel, Switzerland), 2020-11, Vol.25 (22), p.5271

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

Caffeic acid and related natural compounds were previously described as Leishmania amazonensis arginase (L-ARG) inhibitors, and against the whole parasite in vitro. In this study, we tested cinnamides that were previously synthesized to target human arginase. The compound caffeic acid phenethyl amide (CAPA), a weak inhibitor of human arginase (IC50...

Alternative Titles

Full title

Cinnamides Target Leishmania amazonensis Arginase Selectively

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_beefaca560cd4ecda25f10f910ca0fd9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_beefaca560cd4ecda25f10f910ca0fd9

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules25225271

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