Cinnamides Target Leishmania amazonensis Arginase Selectively
Cinnamides Target Leishmania amazonensis Arginase Selectively
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Publisher
Switzerland: MDPI
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Language
English
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Publisher
Switzerland: MDPI
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Scope and Contents
Contents
Caffeic acid and related natural compounds were previously described as Leishmania amazonensis arginase (L-ARG) inhibitors, and against the whole parasite in vitro. In this study, we tested cinnamides that were previously synthesized to target human arginase. The compound caffeic acid phenethyl amide (CAPA), a weak inhibitor of human arginase (IC50...
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Full title
Cinnamides Target Leishmania amazonensis Arginase Selectively
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TN_cdi_doaj_primary_oai_doaj_org_article_beefaca560cd4ecda25f10f910ca0fd9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_beefaca560cd4ecda25f10f910ca0fd9
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules25225271