Genome-wide association and transcriptome studies identify target genes and risk loci for breast can...
Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
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Author / Creator
Ferreira, Manuel A. , Andrulis, Irene L. , Anton-Culver, Hoda , Aronson, Kristan J. , Barnes, Daniel R. , Beckmann, Matthias W. , Behrens, Sabine , Bermisheva, Marina , Bogdanova, Natalia V. , Bojesen, Stig E. , Bolla, Manjeet K. , Brauch, Hiltrud , Campa, Daniele , Campbell, Ian , Canzian, Federico , Carter, Jonathan , Castelao, Jose E. , Chang-Claude, Jenny , Couch, Fergus J. , Cox, Angela , Cross, Simon S. , de la Hoya, Miguel , Dennis, Joe , Devilee, Peter , Dörk, Thilo , Ejlertsen, Bent , Engel, Christoph , Eriksson, Mikael , Fletcher, Olivia , Flyger, Henrik , Frost, Debra , Gabrielson, Marike , Gapstur, Susan M. , Garber, Judy , García-Sáenz, José A. , Giles, Graham G. , Glendon, Gord , Godwin, Andrew K. , González-Neira, Anna , Gronwald, Jacek , Guénel, Pascal , Hall, Per , Hamann, Ute , He, Wei , Hulick, Peter J. , Humphreys, Keith , Isaacs, Claudine , Jakimovska, Milena , Jakubowska, Anna , James, Paul A. , John, Esther M. , Johnson, Nichola , Karlan, Beth Y. , Khusnutdinova, Elza , Kiiski, Johanna I. , Jones, Michael E. , Konstantopoulou, Irene , Laitman, Yael , Lambrechts, Diether , Lazaro, Conxi , Lindström, Sara , Manoochehri, Mehdi , Margolin, Sara , McGuffog, Lesley , Michailidou, Kyriaki , Montagna, Marco , Moreno, Fernando , Moserle, Lidia , Nevelsteen, Ines , Nussbaum, Robert L. , Offit, Kenneth , Olah, Edith , Olopade, Olufunmilayo I. , Osorio, Ana , Park-Simon, Tjoung-Won , Pedersen, Inge Sokilde , Peixoto, Ana , Peterlongo, Paolo , Poppe, Bruce , Presneau, Nadege , Risch, Harvey A. , Saloustros, Emmanouil , Sanden, Kristin , Simard, Jacques , Singer, Christian F. , Soucy, Penny , Spinelli, John J. , Spurdle, Amanda B. , Taylor, Jack A. , Thöne, Kathrin , Toland, Amanda E. , Tung, Nadine , Vachon, Celine M. , van Asperen, Christi J. , van Rensburg, Elizabeth J. , Weitzel, Jeffrey N. , Winqvist, Robert , Yannoukakos, Drakoulis , Zheng, Wei , Beesley, Jonathan , BCFR Investigators , ABCTB Investigators , HEBON Investigators , GC-HBOC Study Collaborators , GEMO Study Collaborators , EMBRACE Collaborators , EMBRACE , Strategiska forskningsområden (SFO) , Bröstcancer-genetik , Lunds Melanomstudiegrupp , EpiHealth: Epidemiology for Health , Section I , Strategic research areas (SRA) , Department of Clinical Sciences, Lund , Familial Breast Cancer , Lund University , Sektion V , Profile areas and other strong research environments , Section V , Kirurgi, Lund , Breastcancer-genetics , Tumor microenvironment , Medicinsk onkologi , Faculty of Medicine , Medicinska fakulteten , Institutionen för kliniska vetenskaper, Lund , Lund Melanoma Study Group , Lunds universitet , Familjär bröstcancer , Sektion I , Surgery (Lund) , Tumörmikromiljö , Profilområden och andra starka forskningsmiljöer and Medical oncology
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Genome-wide association studies (GWAS) have identified more than 170 breast cancer susceptibility loci. Here we hypothesize that some risk-associated variants might act in non-breast tissues, specifically adipose tissue and immune cells from blood and spleen. Using expression quantitative trait loci (eQTL) reported in these tissues, we identify 26...
Alternative Titles
Full title
Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
Authors, Artists and Contributors
Author / Creator
Andrulis, Irene L.
Anton-Culver, Hoda
Aronson, Kristan J.
Barnes, Daniel R.
Beckmann, Matthias W.
Behrens, Sabine
Bermisheva, Marina
Bogdanova, Natalia V.
Bojesen, Stig E.
Bolla, Manjeet K.
Brauch, Hiltrud
Campa, Daniele
Campbell, Ian
Canzian, Federico
Carter, Jonathan
Castelao, Jose E.
Chang-Claude, Jenny
Couch, Fergus J.
Cox, Angela
Cross, Simon S.
de la Hoya, Miguel
Dennis, Joe
Devilee, Peter
Dörk, Thilo
Ejlertsen, Bent
Engel, Christoph
Eriksson, Mikael
Fletcher, Olivia
Flyger, Henrik
Frost, Debra
Gabrielson, Marike
Gapstur, Susan M.
Garber, Judy
García-Sáenz, José A.
Giles, Graham G.
Glendon, Gord
Godwin, Andrew K.
González-Neira, Anna
Gronwald, Jacek
Guénel, Pascal
Hall, Per
Hamann, Ute
He, Wei
Hulick, Peter J.
Humphreys, Keith
Isaacs, Claudine
Jakimovska, Milena
Jakubowska, Anna
James, Paul A.
John, Esther M.
Johnson, Nichola
Karlan, Beth Y.
Khusnutdinova, Elza
Kiiski, Johanna I.
Jones, Michael E.
Konstantopoulou, Irene
Laitman, Yael
Lambrechts, Diether
Lazaro, Conxi
Lindström, Sara
Manoochehri, Mehdi
Margolin, Sara
McGuffog, Lesley
Michailidou, Kyriaki
Montagna, Marco
Moreno, Fernando
Moserle, Lidia
Nevelsteen, Ines
Nussbaum, Robert L.
Offit, Kenneth
Olah, Edith
Olopade, Olufunmilayo I.
Osorio, Ana
Park-Simon, Tjoung-Won
Pedersen, Inge Sokilde
Peixoto, Ana
Peterlongo, Paolo
Poppe, Bruce
Presneau, Nadege
Risch, Harvey A.
Saloustros, Emmanouil
Sanden, Kristin
Simard, Jacques
Singer, Christian F.
Soucy, Penny
Spinelli, John J.
Spurdle, Amanda B.
Taylor, Jack A.
Thöne, Kathrin
Toland, Amanda E.
Tung, Nadine
Vachon, Celine M.
van Asperen, Christi J.
van Rensburg, Elizabeth J.
Weitzel, Jeffrey N.
Winqvist, Robert
Yannoukakos, Drakoulis
Zheng, Wei
Beesley, Jonathan
BCFR Investigators
ABCTB Investigators
HEBON Investigators
GC-HBOC Study Collaborators
GEMO Study Collaborators
EMBRACE Collaborators
EMBRACE
Strategiska forskningsområden (SFO)
Bröstcancer-genetik
Lunds Melanomstudiegrupp
EpiHealth: Epidemiology for Health
Section I
Strategic research areas (SRA)
Department of Clinical Sciences, Lund
Familial Breast Cancer
Lund University
Sektion V
Profile areas and other strong research environments
Section V
Kirurgi, Lund
Breastcancer-genetics
Tumor microenvironment
Medicinsk onkologi
Faculty of Medicine
Medicinska fakulteten
Institutionen för kliniska vetenskaper, Lund
Lund Melanoma Study Group
Lunds universitet
Familjär bröstcancer
Sektion I
Surgery (Lund)
Tumörmikromiljö
Profilområden och andra starka forskningsmiljöer
Medical oncology
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_bf21d4862d3747ff97f6117d701a4866
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bf21d4862d3747ff97f6117d701a4866
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-08053-5
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