IPSC derived cardiac fibroblasts of DMD patients show compromised actin microfilaments, metabolic sh...
IPSC derived cardiac fibroblasts of DMD patients show compromised actin microfilaments, metabolic shift and pro-fibrotic phenotype
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England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Duchenne muscular dystrophy (DMD) is a severe form of muscular dystrophy caused by mutations in the dystrophin gene. We characterized which isoforms of dystrophin were expressed by human induced pluripotent stem cell (hiPSC)-derived cardiac fibroblasts obtained from control and DMD patients. Distinct dystrophin isoforms were observed; however, high...
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IPSC derived cardiac fibroblasts of DMD patients show compromised actin microfilaments, metabolic shift and pro-fibrotic phenotype
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TN_cdi_doaj_primary_oai_doaj_org_article_bf3a762253b14d5b8a3a2000997579d2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bf3a762253b14d5b8a3a2000997579d2
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ISSN
1745-6150
E-ISSN
1745-6150
DOI
10.1186/s13062-023-00398-2
