The discovery and structural basis of two distinct state-dependent inhibitors of BamA
The discovery and structural basis of two distinct state-dependent inhibitors of BamA
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Author / Creator
Sun, Dawei , Storek, Kelly M. , Tegunov, Dimitry , Yang, Ying , Arthur, Christopher P. , Johnson, Matthew , Quinn, John G. , Liu, Weijing , Han, Guanghui , Girgis, Hany S. , Alexander, Mary Kate , Murchison, Austin K. , Shriver, Stephanie , Tam, Christine , Ijiri, Hiroshi , Inaba, Hiroko , Sano, Tatsuya , Yanagida, Hayato , Nishikawa, Junichi , Heise, Christopher E. , Fairbrother, Wayne J. , Tan, Man-Wah , Skelton, Nicholas , Sandoval, Wendy , Sellers, Benjamin D. , Ciferri, Claudio , Smith, Peter A. , Reid, Patrick C. , Cunningham, Christian N. , Rutherford, Steven T. and Payandeh, Jian
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
BamA is the central component of the essential β-barrel assembly machine (BAM), a conserved multi-subunit complex that dynamically inserts and folds β-barrel proteins into the outer membrane of Gram-negative bacteria. Despite recent advances in our mechanistic and structural understanding of BamA, there are few potent and selective tool molecules t...
Alternative Titles
Full title
The discovery and structural basis of two distinct state-dependent inhibitors of BamA
Authors, Artists and Contributors
Author / Creator
Storek, Kelly M.
Tegunov, Dimitry
Yang, Ying
Arthur, Christopher P.
Johnson, Matthew
Quinn, John G.
Liu, Weijing
Han, Guanghui
Girgis, Hany S.
Alexander, Mary Kate
Murchison, Austin K.
Shriver, Stephanie
Tam, Christine
Ijiri, Hiroshi
Inaba, Hiroko
Sano, Tatsuya
Yanagida, Hayato
Nishikawa, Junichi
Heise, Christopher E.
Fairbrother, Wayne J.
Tan, Man-Wah
Skelton, Nicholas
Sandoval, Wendy
Sellers, Benjamin D.
Ciferri, Claudio
Smith, Peter A.
Reid, Patrick C.
Cunningham, Christian N.
Rutherford, Steven T.
Payandeh, Jian
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_bf48c6d78a39468c81c644c4c61faa56
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bf48c6d78a39468c81c644c4c61faa56
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-52512-1
