In vivo structure and dynamics of the SARS-CoV-2 RNA genome
In vivo structure and dynamics of the SARS-CoV-2 RNA genome
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Author / Creator
Zhang, Yan , Huang, Kun , Xie, Dejian , Lau, Jian You , Shen, Wenlong , Li, Ping , Wang, Dong , Zou, Zhong , Shi, Shu , Ren, Hongguang , Wang, Youliang , Mao, Youzhi , Jin, Meilin , Kudla, Grzegorz and Zhao, Zhihu
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The dynamics of SARS-CoV-2 RNA structure and their functional relevance are largely unknown. Here we develop a simplified SPLASH assay and comprehensively map the in vivo RNA-RNA interactome of SARS-CoV-2 genome across viral life cycle. We report canonical and alternative structures including 5′-UTR and 3′-UTR, frameshifting element (FSE) pseudokno...
Alternative Titles
Full title
In vivo structure and dynamics of the SARS-CoV-2 RNA genome
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_bf4d385818f044d6a07123d71479e0cd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bf4d385818f044d6a07123d71479e0cd
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25999-1
