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Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection d...

Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection d...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bf69c279f51a438a855d5773df6f0873

Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy

About this item

Full title

Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-10, Vol.11 (1), p.5278-13, Article 5278

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

There are no licensed therapeutics or vaccines available against Zika virus (ZIKV) to counteract its potential for congenital disease. Antibody-based countermeasures targeting the ZIKV envelope protein have been hampered by concerns for cross-reactive responses that induce antibody-dependent enhancement (ADE) of heterologous flavivirus infection. N...

Alternative Titles

Full title

Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_bf69c279f51a438a855d5773df6f0873

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bf69c279f51a438a855d5773df6f0873

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-19096-y

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