Therapeutic efficacy of human adipose mesenchymal stem cells in Crohn’s colon fibrosis is improved b...
Therapeutic efficacy of human adipose mesenchymal stem cells in Crohn’s colon fibrosis is improved by IFN-γ and kynurenic acid priming through indoleamine 2,3-dioxygenase-1 signaling
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Ye, Yixin , Zhang, Xiaomei , Su, Dongsheng , Ren, Yushuang , Cheng, Fuyi , Yao, Yunqi , Shi, Gang , Ji, Yanhong , Chen, Shuang , Shi, Pengyi , Dai, Lei , Su, Xiaolan and Deng, Hongxin
Publisher
London: BioMed Central
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Language
English
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Publisher
London: BioMed Central
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Background Inflammatory bowel diseases (IBD) are chronic relapsing–remitting inflammatory diseases of the gastrointestinal tract that are typically categorized into two subtypes: Crohn's disease (CD) and ulcerative colitis (UC). Although MSCs therapy has achieved encouraging outcomes in IBD therapy, objective responses are limited in colon fibrosis...
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Full title
Therapeutic efficacy of human adipose mesenchymal stem cells in Crohn’s colon fibrosis is improved by IFN-γ and kynurenic acid priming through indoleamine 2,3-dioxygenase-1 signaling
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TN_cdi_doaj_primary_oai_doaj_org_article_bf7abc0cd96149778e9399d0c7cdb654
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bf7abc0cd96149778e9399d0c7cdb654
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ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-022-03157-8
