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The RNA sensor MDA5 detects SARS-CoV-2 infection

The RNA sensor MDA5 detects SARS-CoV-2 infection

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bf7b2861bd4e49ec90699e30b9ce5848

The RNA sensor MDA5 detects SARS-CoV-2 infection

About this item

Full title

The RNA sensor MDA5 detects SARS-CoV-2 infection

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-07, Vol.11 (1), p.13638-13638, Article 13638

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Human cells respond to infection by SARS-CoV-2, the virus that causes COVID-19, by producing cytokines including type I and III interferons (IFNs) and proinflammatory factors such as IL6 and TNF. IFNs can limit SARS-CoV-2 replication but cytokine imbalance contributes to severe COVID-19. We studied how cells detect SARS-CoV-2 infection. We report t...

Alternative Titles

Full title

The RNA sensor MDA5 detects SARS-CoV-2 infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_bf7b2861bd4e49ec90699e30b9ce5848

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bf7b2861bd4e49ec90699e30b9ce5848

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-92940-3

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