Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzh...
Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease
About this item
Full title
Author / Creator
Chen, Hsiang-Han , Eteleeb, Abdallah , Wang, Ciyang , Fernandez, Maria Victoria , Budde, John P. , Bergmann, Kristy , Norton, Joanne , Wang, Fengxian , Ebl, Curtis , Morris, John C. , Perrin, Richard J. , Bateman, Randall J. , McDade, Eric , Xiong, Chengjie , Goate, Alison , Farlow, Martin , Chhatwal, Jasmeer , Schofield, Peter R. , Chui, Helena , Harari, Oscar , Cruchaga, Carlos , Ibanez, Laura and Dominantly Inherited Alzheimer Network
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Autosomal-dominant Alzheimer's disease (ADAD) is caused by pathogenic mutations in APP, PSEN1, and PSEN2, which usually lead to an early age at onset (< 65). Circular RNAs are a family of non-coding RNAs highly expressed in the nervous system and especially in synapses. We aimed to investigate differences in brain gene expression of linear and circ...
Alternative Titles
Full title
Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease
Authors, Artists and Contributors
Author / Creator
Eteleeb, Abdallah
Wang, Ciyang
Fernandez, Maria Victoria
Budde, John P.
Bergmann, Kristy
Norton, Joanne
Wang, Fengxian
Ebl, Curtis
Morris, John C.
Perrin, Richard J.
Bateman, Randall J.
McDade, Eric
Xiong, Chengjie
Goate, Alison
Farlow, Martin
Chhatwal, Jasmeer
Schofield, Peter R.
Chui, Helena
Harari, Oscar
Cruchaga, Carlos
Ibanez, Laura
Dominantly Inherited Alzheimer Network
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_bf883b27c2594839a9332c5dd57be351
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bf883b27c2594839a9332c5dd57be351
Other Identifiers
ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-022-01328-5
