Neurosteroid allopregnanolone (3α,5α-THP) inhibits inflammatory signals induced by activated MyD88-d...
Neurosteroid allopregnanolone (3α,5α-THP) inhibits inflammatory signals induced by activated MyD88-dependent toll-like receptors
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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We have shown that endogenous neurosteroids, including pregnenolone and 3α,5α-THP inhibit toll-like receptor 4 (TLR4) signal activation in mouse macrophages and the brain of alcohol-preferring (P) rat, which exhibits innate TLR4 signal activation. The current studies were designed to examine whether other activated TLR signals are similarly inhibit...
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Neurosteroid allopregnanolone (3α,5α-THP) inhibits inflammatory signals induced by activated MyD88-dependent toll-like receptors
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TN_cdi_doaj_primary_oai_doaj_org_article_bf981cc862c742bd85a7e2bd2d048b08
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bf981cc862c742bd85a7e2bd2d048b08
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2158-3188
E-ISSN
2158-3188
DOI
10.1038/s41398-021-01266-1
