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Chemical fixation creates nanoscale clusters on the cell surface by aggregating membrane proteins

Chemical fixation creates nanoscale clusters on the cell surface by aggregating membrane proteins

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bfa243552518430bb1689a77cc957800

Chemical fixation creates nanoscale clusters on the cell surface by aggregating membrane proteins

About this item

Full title

Chemical fixation creates nanoscale clusters on the cell surface by aggregating membrane proteins

Publisher

London: Nature Publishing Group UK

Journal title

Communications biology, 2022-05, Vol.5 (1), p.487-487, Article 487

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Chemical fixations have been thought to preserve the structures of the cells or tissues. However, given that the fixatives create crosslinks or aggregate proteins, there is a possibility that these fixatives create nanoscale artefacts by aggregation of membrane proteins which move around freely to some extent on the cell surface. Despite this, litt...

Alternative Titles

Full title

Chemical fixation creates nanoscale clusters on the cell surface by aggregating membrane proteins

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_bfa243552518430bb1689a77cc957800

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bfa243552518430bb1689a77cc957800

Other Identifiers

ISSN

2399-3642

E-ISSN

2399-3642

DOI

10.1038/s42003-022-03437-2

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