Punicalagin Induces Nrf2/HO-1 Expression via Upregulation of PI3K/AKT Pathway and Inhibits LPS-Induc...
Punicalagin Induces Nrf2/HO-1 Expression via Upregulation of PI3K/AKT Pathway and Inhibits LPS-Induced Oxidative Stress in RAW264.7 Macrophages
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Author / Creator
Xu, Jianqin , Liu, Fenghua , Yin, Peng , Wan, Changrong , He, Shasha , Li, Deyin , Hou, Xiaolin , Li, Hongquan , Xu, Xiaolong and Liu, Mingjiang
Publisher
Cairo, Egypt: Hindawi Limiteds
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Language
English
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Publisher
Cairo, Egypt: Hindawi Limiteds
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Contents
Reactive oxygen species (ROS) and oxidative stress are thought to play a central role in potentiating macrophage activation, causing excessive inflammation, tissue damage, and sepsis. Recently, we have shown that punicalagin (PUN) exhibits anti-inflammatory activity in LPS-stimulated macrophages. However, the potential antioxidant effects of PUN in...
Alternative Titles
Full title
Punicalagin Induces Nrf2/HO-1 Expression via Upregulation of PI3K/AKT Pathway and Inhibits LPS-Induced Oxidative Stress in RAW264.7 Macrophages
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_bfa9befc76e040f08508f9a2281ca8d6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bfa9befc76e040f08508f9a2281ca8d6
Other Identifiers
ISSN
0962-9351
E-ISSN
1466-1861
DOI
10.1155/2015/380218
