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Interleukin-27 Regulates the Function of the Gastrointestinal Epithelial Barrier in a Human Tissue-D...

Interleukin-27 Regulates the Function of the Gastrointestinal Epithelial Barrier in a Human Tissue-D...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bfd3bdd5fc0849e49ba926846b57a200

Interleukin-27 Regulates the Function of the Gastrointestinal Epithelial Barrier in a Human Tissue-Derived Organoid Model

About this item

Full title

Interleukin-27 Regulates the Function of the Gastrointestinal Epithelial Barrier in a Human Tissue-Derived Organoid Model

Publisher

Switzerland: MDPI AG

Journal title

Biology (Basel, Switzerland), 2022-03, Vol.11 (3), p.427

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

A treatment with direct healing effects on the gastrointestinal epithelial barrier is desirable for inflammatory bowel disease (IBD). Interleukin-27 (IL-27) is an immunoregulatory cytokine, and oral delivery is an effective treatment in murine models of IBD. We aimed to define IL-27 effects on the human gastrointestinal epithelial barrier. We chara...

Alternative Titles

Full title

Interleukin-27 Regulates the Function of the Gastrointestinal Epithelial Barrier in a Human Tissue-Derived Organoid Model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_bfd3bdd5fc0849e49ba926846b57a200

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bfd3bdd5fc0849e49ba926846b57a200

Other Identifiers

ISSN

2079-7737

E-ISSN

2079-7737

DOI

10.3390/biology11030427

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