Evaluation of body-surface-area adjusted dosing of high-dose methotrexate by population pharmacokine...
Evaluation of body-surface-area adjusted dosing of high-dose methotrexate by population pharmacokinetics in a large cohort of cancer patients
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background The aim of this study was to identify sources of variability including patient gender and body surface area (BSA) in pharmacokinetic (PK) exposure for high-dose methotrexate (MTX) continuous infusion in a large cohort of patients with hematological and solid malignancies. Methods We conducted a retrospective PK analysis of MTX plasma con...
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Evaluation of body-surface-area adjusted dosing of high-dose methotrexate by population pharmacokinetics in a large cohort of cancer patients
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TN_cdi_doaj_primary_oai_doaj_org_article_c016e179215a4feb8bb8ff3b55ed3ebb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c016e179215a4feb8bb8ff3b55ed3ebb
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-021-08443-x
