Antibodies to the RBD of SARS-CoV-2 spike mediate productive infection of primary human macrophages
Antibodies to the RBD of SARS-CoV-2 spike mediate productive infection of primary human macrophages
About this item
Full title
Author / Creator
Pickering, Suzanne , Wilson, Harry , Bravo, Enrico , Perera, Marianne R. , Seow, Jeffrey , Graham, Carl , Almeida, Nathalia , Fotopoulos, Lazaros , Williams, Thomas , Moitra, Atlanta , Winstone, Helena , Nissen, Tinne A. D. , Galão, Rui Pedro , Snell, Luke B. , Doores, Katie J. , Malim, Michael H. and Neil, Stuart J. D.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The role of myeloid cells in the pathogenesis of SARS-CoV-2 is well established, in particular as drivers of cytokine production and systemic inflammation characteristic of severe COVID-19. However, the potential for myeloid cells to act as bona fide targets of productive SARS-CoV-2 infection, and the specifics of entry, remain unclear. Using a pan...
Alternative Titles
Full title
Antibodies to the RBD of SARS-CoV-2 spike mediate productive infection of primary human macrophages
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c018715cd41f4ea5a9110241211f4c0e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c018715cd41f4ea5a9110241211f4c0e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-54458-w
