Munc13-1 and Munc18-1 together prevent NSF-dependent de-priming of synaptic vesicles
Munc13-1 and Munc18-1 together prevent NSF-dependent de-priming of synaptic vesicles
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Synaptic transmission requires a stable pool of release-ready (primed) vesicles. Here we show that two molecules involved in SNARE-complex assembly, Munc13-1 and Munc18-1, together stabilize release-ready vesicles by preventing de-priming. Replacing neuronal Munc18-1 by a non-neuronal isoform Munc18-2 (Munc18-1/2SWAP) supports activity-dependent pr...
Alternative Titles
Full title
Munc13-1 and Munc18-1 together prevent NSF-dependent de-priming of synaptic vesicles
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c04e466c0f2a462ab9e60635e82e61e1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c04e466c0f2a462ab9e60635e82e61e1
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15915
