NPTX2 and cognitive dysfunction in Alzheimer’s Disease
NPTX2 and cognitive dysfunction in Alzheimer’s Disease
About this item
Full title
Author / Creator
Xiao, Mei-Fang , Xu, Desheng , Craig, Michael T , Pelkey, Kenneth A , Chien, Chun-Che , Shi, Yang , Zhang, Juhong , Resnick, Susan , Pletnikova, Olga , Salmon, David , Brewer, James , Edland, Steven , Wegiel, Jerzy , Tycko, Benjamin , Savonenko, Alena , Reeves, Roger H , Troncoso, Juan C , McBain, Chris J , Galasko, Douglas and Worley, Paul F
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
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Publication information
Publisher
England: eLife Sciences Publications Ltd
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Scope and Contents
Contents
Memory loss in Alzheimer’s disease (AD) is attributed to pervasive weakening and loss of synapses. Here, we present findings supporting a special role for excitatory synapses connecting pyramidal neurons of the hippocampus and cortex with fast-spiking parvalbumin (PV) interneurons that control network excitability and rhythmicity. Excitatory synaps...
Alternative Titles
Full title
NPTX2 and cognitive dysfunction in Alzheimer’s Disease
Authors, Artists and Contributors
Author / Creator
Xu, Desheng
Craig, Michael T
Pelkey, Kenneth A
Chien, Chun-Che
Shi, Yang
Zhang, Juhong
Resnick, Susan
Pletnikova, Olga
Salmon, David
Brewer, James
Edland, Steven
Wegiel, Jerzy
Tycko, Benjamin
Savonenko, Alena
Reeves, Roger H
Troncoso, Juan C
McBain, Chris J
Galasko, Douglas
Worley, Paul F
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c08345d0049e4dd1b942103924533d4a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c08345d0049e4dd1b942103924533d4a
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.23798
