Cotransfected human chondrocytes: over-expression of IGF-I and SOX9 enhances the synthesis of cartil...
Cotransfected human chondrocytes: over-expression of IGF-I and SOX9 enhances the synthesis of cartilage matrix components collagen-II and glycosaminoglycans
About this item
Full title
Author / Creator
Publisher
Brazil: Associacao Brasileira de Divulgacao Cientifica (ABDC)
Journal title
Language
English
Formats
Publication information
Publisher
Brazil: Associacao Brasileira de Divulgacao Cientifica (ABDC)
Subjects
More information
Scope and Contents
Contents
Damage to cartilage causes a loss of type II collagen (Col-II) and glycosaminoglycans (GAG). To restore the original cartilage architecture, cell factors that stimulate Col-II and GAG production are needed. Insulin-like growth factor I (IGF-I) and transcription factor SOX9are essential for the synthesis of cartilage matrix, chondrocyte proliferatio...
Alternative Titles
Full title
Cotransfected human chondrocytes: over-expression of IGF-I and SOX9 enhances the synthesis of cartilage matrix components collagen-II and glycosaminoglycans
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c08a2e0042864949b935929b4f4c8407
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c08a2e0042864949b935929b4f4c8407
Other Identifiers
ISSN
0100-879X,1414-431X
E-ISSN
1414-431X
DOI
10.1590/1414-431X20154732
