Proton export upregulates aerobic glycolysis
Proton export upregulates aerobic glycolysis
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Aggressive cancers commonly ferment glucose to lactic acid at high rates, even in the presence of oxygen. This is known as aerobic glycolysis, or the "Warburg Effect." It is widely assumed that this is a consequence of the upregulation of glycolytic enzymes. Oncogenic drivers can increase the expression of most proteins in the glycolytic pathway, i...
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Proton export upregulates aerobic glycolysis
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TN_cdi_doaj_primary_oai_doaj_org_article_c08b6bd921534c2bac3f3262ad7ecba1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c08b6bd921534c2bac3f3262ad7ecba1
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ISSN
1741-7007
E-ISSN
1741-7007
DOI
10.1186/s12915-022-01340-0
