Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute my...
Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Translocations of the Mixed Lineage Leukemia (MLL) gene occur in a subset (5%) of acute myeloid leukemias (AML), and in mixed phenotype acute leukemias in infancy - a disease with extremely poor prognosis. Animal model systems show that MLL gain of function mutations may contribute to leukemogenesis. Wild-type (wt) MLL possesses histone methyltrans...
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Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia
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TN_cdi_doaj_primary_oai_doaj_org_article_c097646eb03647afae03ee3bf6ba2d8b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c097646eb03647afae03ee3bf6ba2d8b
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/1476-4598-8-86
