Analysis of asymptomatic Drosophila models for ALS and SMA reveals convergent impact on functional p...
Analysis of asymptomatic Drosophila models for ALS and SMA reveals convergent impact on functional protein complexes linked to neuro-muscular degeneration
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London: BioMed Central Ltd
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Language
English
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London: BioMed Central Ltd
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Spinal Muscular Atrophy (SMA) and Amyotrophic Lateral Sclerosis (ALS) share phenotypic and molecular commonalities, including the fact that they can be caused by mutations in ubiquitous proteins involved in RNA metabolism, namely SMN, TDP-43 and FUS. Although this suggests the existence of common disease mechanisms, there is currently no model to e...
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Analysis of asymptomatic Drosophila models for ALS and SMA reveals convergent impact on functional protein complexes linked to neuro-muscular degeneration
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TN_cdi_doaj_primary_oai_doaj_org_article_c0eb6c41b5cf40b5b61bd6310c394c4f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c0eb6c41b5cf40b5b61bd6310c394c4f
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ISSN
1471-2164
E-ISSN
1471-2164
DOI
10.1186/s12864-023-09562-4
