HPV-16 E7 expression up-regulates phospholipase D activity and promotes rapamycin resistance in a pR...
HPV-16 E7 expression up-regulates phospholipase D activity and promotes rapamycin resistance in a pRB-dependent manner
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Human Papillomavirus (HPV) infection is the main risk factor for the development and progression of cervical cancer. HPV-16 E6 and E7 expression is essential for induction and maintenance of the transformed phenotype. These oncoproteins interfere with the function of several intracellular proteins, including those controlling the PI3K/AKT/mTOR path...
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HPV-16 E7 expression up-regulates phospholipase D activity and promotes rapamycin resistance in a pRB-dependent manner
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TN_cdi_doaj_primary_oai_doaj_org_article_c11dee8096b64eedb4a5cf8102b0aff7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c11dee8096b64eedb4a5cf8102b0aff7
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-018-4392-8
