FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x express...
FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression
About this item
Full title
Author / Creator
Puan, Kia Joo , San Luis, Boris , Yusof, Nurhashikin , Kumar, Dilip , Andiappan, Anand Kumar , Lee, Wendy , Cajic, Samanta , Vuckovic, Dragana , Chan, Jing De , Döllner, Tobias , Hou, Han Wei , Jiang, Yunxuan , Tian, Chao , Rapp, Erdmann , Poidinger, Michael , Wang, De Yun , Soranzo, Nicole , Lee, Bernett , Rötzschke, Olaf and the 23andMe Research Team
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Sialyl-Lewis x (sLe
x
, CD15s) is a tetra-saccharide on the surface of leukocytes required for E-selectin-mediated rolling, a prerequisite for leukocytes to migrate out of the blood vessels. Here we show using flow cytometry that sLe
x
expression on basophils and mast cell progenitors depends on fucosyltransferase 6 (
FUT6
). Usin...
Alternative Titles
Full title
FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression
Authors, Artists and Contributors
Author / Creator
San Luis, Boris
Yusof, Nurhashikin
Kumar, Dilip
Andiappan, Anand Kumar
Lee, Wendy
Cajic, Samanta
Vuckovic, Dragana
Chan, Jing De
Döllner, Tobias
Hou, Han Wei
Jiang, Yunxuan
Tian, Chao
Rapp, Erdmann
Poidinger, Michael
Wang, De Yun
Soranzo, Nicole
Lee, Bernett
Rötzschke, Olaf
the 23andMe Research Team
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c143d737821c4b528b01c70d7893f2f4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c143d737821c4b528b01c70d7893f2f4
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-021-02295-8
