Targeting arginase-1 exerts antitumor effects in multiple myeloma and mitigates bortezomib-induced c...
Targeting arginase-1 exerts antitumor effects in multiple myeloma and mitigates bortezomib-induced cardiotoxicity
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Author / Creator
Ramji, Kavita , Grzywa, Tomasz M. , Sosnowska, Anna , Paterek, Aleksandra , Okninska, Marta , Pilch, Zofia , Barankiewicz, Joanna , Garbicz, Filip , Borg, Katarzyna , Bany-Laszewicz, Urszula , Zerrouqi, Abdesamad , Pyrzynska, Beata , Rodziewicz-Lurzynska, Anna , Papiernik, Diana , Sklepkiewicz, Piotr , Kedzierska, Hanna , Staruch, Adam , Sadowski, Radoslaw , Ciepiela, Olga , Lech-Maranda, Ewa , Juszczynski, Przemyslaw , Mackiewicz, Urszula , Maczewski, Michal , Nowis, Dominika and Golab, Jakub
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Multiple myeloma (MM) remains an incurable malignancy of plasma cells despite constantly evolving therapeutic approaches including various types of immunotherapy. Increased arginase activity has been associated with potent suppression of T-cell immune responses in different types of cancer. Here, we investigated the role of arginase 1 (ARG1) in Vκ*...
Alternative Titles
Full title
Targeting arginase-1 exerts antitumor effects in multiple myeloma and mitigates bortezomib-induced cardiotoxicity
Authors, Artists and Contributors
Author / Creator
Grzywa, Tomasz M.
Sosnowska, Anna
Paterek, Aleksandra
Okninska, Marta
Pilch, Zofia
Barankiewicz, Joanna
Garbicz, Filip
Borg, Katarzyna
Bany-Laszewicz, Urszula
Zerrouqi, Abdesamad
Pyrzynska, Beata
Rodziewicz-Lurzynska, Anna
Papiernik, Diana
Sklepkiewicz, Piotr
Kedzierska, Hanna
Staruch, Adam
Sadowski, Radoslaw
Ciepiela, Olga
Lech-Maranda, Ewa
Juszczynski, Przemyslaw
Mackiewicz, Urszula
Maczewski, Michal
Nowis, Dominika
Golab, Jakub
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c1756db456d04ea59f57f4c24f50c6c9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c1756db456d04ea59f57f4c24f50c6c9
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-24137-1
