SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target
About this item
Full title
Author / Creator
Yuan, Shuofeng , Chu, Hin , Chan, Jasper Fuk-Woo , Ye, Zi-Wei , Wen, Lei , Yan, Bingpeng , Lai, Pok-Man , Tee, Kah-Meng , Huang, Jingjing , Chen, Dongdong , Li, Cun , Zhao, Xiaoyu , Yang, Dong , Chiu, Man Chun , Yip, Cyril , Poon, Vincent Kwok-Man , Chan, Chris Chung-Sing , Sze, Kong-Hung , Zhou, Jie , Chan, Ivy Hau-Yee , Kok, Kin-Hang , To, Kelvin Kai-Wang , Kao, Richard Yi-Tsun , Lau, Johnson Yiu-Nam , Jin, Dong-Yan , Perlman, Stanley and Yuen, Kwok-Yung
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Viruses are obligate intracellular microbes that exploit the host metabolic machineries to meet their biosynthetic demands, making these host pathways potential therapeutic targets. Here, by exploring a lipid library, we show that AM580, a retinoid derivative and RAR-α agonist, is highly potent in interrupting the life cycle of diverse viruses incl...
Alternative Titles
Full title
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target
Authors, Artists and Contributors
Author / Creator
Chu, Hin
Chan, Jasper Fuk-Woo
Ye, Zi-Wei
Wen, Lei
Yan, Bingpeng
Lai, Pok-Man
Tee, Kah-Meng
Huang, Jingjing
Chen, Dongdong
Li, Cun
Zhao, Xiaoyu
Yang, Dong
Chiu, Man Chun
Yip, Cyril
Poon, Vincent Kwok-Man
Chan, Chris Chung-Sing
Sze, Kong-Hung
Zhou, Jie
Chan, Ivy Hau-Yee
Kok, Kin-Hang
To, Kelvin Kai-Wang
Kao, Richard Yi-Tsun
Lau, Johnson Yiu-Nam
Jin, Dong-Yan
Perlman, Stanley
Yuen, Kwok-Yung
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c1c5fe348ab54b8eb38874751717d9b6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c1c5fe348ab54b8eb38874751717d9b6
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-08015-x
