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Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations

Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c1c9a8215f07411f822a4bb11aeab073

Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations

About this item

Full title

Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations

Publisher

London: Nature Publishing Group UK

Journal title

Molecular systems biology, 2022-03, Vol.18 (3), p.e10588-n/a

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The cell stress‐responsive transcription factor p53 influences the expression of its target genes and subsequent cellular responses based in part on its dynamics (changes in level over time). The mechanisms decoding p53 dynamics into subsequent target mRNA and protein dynamics remain unclear. We systematically quantified p53 target mRNA and protein...

Alternative Titles

Full title

Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c1c9a8215f07411f822a4bb11aeab073

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c1c9a8215f07411f822a4bb11aeab073

Other Identifiers

ISSN

1744-4292

E-ISSN

1744-4292

DOI

10.15252/msb.202110588

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