Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations
Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The cell stress‐responsive transcription factor p53 influences the expression of its target genes and subsequent cellular responses based in part on its dynamics (changes in level over time). The mechanisms decoding p53 dynamics into subsequent target mRNA and protein dynamics remain unclear. We systematically quantified p53 target mRNA and protein...
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Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations
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TN_cdi_doaj_primary_oai_doaj_org_article_c1c9a8215f07411f822a4bb11aeab073
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c1c9a8215f07411f822a4bb11aeab073
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ISSN
1744-4292
E-ISSN
1744-4292
DOI
10.15252/msb.202110588