Design and synthesis of novel anti-urease imidazothiazole derivatives with promising antibacterial a...
Design and synthesis of novel anti-urease imidazothiazole derivatives with promising antibacterial activity against Helicobacter pylori
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Public Library of Science (PLoS)
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English
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Public Library of Science (PLoS)
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Urease enzyme is a known therapeutic drug target for treatment of Helicobacter pylori infection due to its role in settlement and growth in gastric mucosa. In this study, we designed a new series of sulfonates and sulfamates bearing imidazo[2,1-b]thiazole scaffold that exhibit a potent inhibitory activity of urease enzyme. The most potent compound...
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Design and synthesis of novel anti-urease imidazothiazole derivatives with promising antibacterial activity against Helicobacter pylori
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TN_cdi_doaj_primary_oai_doaj_org_article_c1f3213c35704221a27d563ddad21e15
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c1f3213c35704221a27d563ddad21e15
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1932-6203
