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Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disea...

Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disea...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c22e81f057bd44ef857ef1b82f628c5a

Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Age-related changes to the genome-wide DNA methylation (DNAm) pattern observed in blood are well-documented. Clonal hematopoiesis of indeterminate potential (CHIP), characterized by the age-related acquisition and expansion of leukemogenic mutations in hematopoietic stem cells (HSCs), is associated with blood cancer and coronary artery disease (CAD...

Alternative Titles

Full title

Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c22e81f057bd44ef857ef1b82f628c5a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c22e81f057bd44ef857ef1b82f628c5a

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-33093-3

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