Identification of nine new susceptibility loci for endometrial cancer

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Identification of nine new susceptibility loci for endometrial cancer

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et al , Faculty of Medicine , Medicinska fakulteten , Strategiska forskningsområden (SFO) , Lunds Melanomstudiegrupp , EpiHealth: Epidemiology for Health , Lund Melanoma Study Group , Institutionen för kliniska vetenskaper, Lund , Strategic research areas (SRA) , Lunds universitet , Department of Clinical Sciences, Lund , Surgery (Lund) , Profilområden och andra starka forskningsmiljöer , Lund University , Sektion V , Profile areas and other strong research environments , Section V , Kirurgi, Lund , O’Mara, Tracy A. , Glubb, Dylan M. , Amant, Frederic , Annibali, Daniela , Ashton, Katie , Attia, John , Auer, Paul L. , Beckmann, Matthias W. , Black, Amanda , Bolla, Manjeet K. , Brauch, Hiltrud , Brenner, Hermann , Brinton, Louise , Buchanan, Daniel D. , Burwinkel, Barbara , Chanock, Stephen J. , Chen, Maxine M. , Cheng, Timothy H. T. , Clarke, Christine L. , Couch, Fergus J. , Cox, Angela , Crous-Bous, Marta , Czene, Kamila , Day, Felix , Dennis, Joe , Depreeuw, Jeroen , Doherty, Jennifer Anne , Dowdy, Sean C. , Dürst, Matthias , Fridley, Brooke L. , Fritschi, Lin , Fung, Jenny , García-Closas, Montserrat , Gaudet, Mia M. , Giles, Graham G. , Gorman, Maggie , Haiman, Christopher A. , Hall, Per , Hankison, Susan E. , Hein, Alexander , Hillemanns, Peter , Hodgson, Shirley , Hoivik, Erling A. , Holliday, Elizabeth G. , Hopper, John L. , Hunter, David J. , Jones, Angela , Krakstad, Camilla , Kristensen, Vessela N. , Lambrechts, Diether , Marchand, Loic Le , Liang, Xiaolin , Lindblom, Annika , Lissowska, Jolanta , Long, Jirong , Magliocco, Anthony M. , Martin, Lynn , McEvoy, Mark , Meindl, Alfons , Michailidou, Kyriaki , Milne, Roger L. , Nassir, Rami , Otton, Geoffrey , Peto, Julian , Pooler, Loreall , Prescott, Jennifer , Proietto, Tony , Rebbeck, Timothy R. , Risch, Harvey A. , Rübner, Matthias , Runnebaum, Ingo , Sarto, Gloria E. , Schumacher, Fredrick , Scott, Rodney J. , Setiawan, V. Wendy , Shah, Mitul , Shu, Xiao-Ou , Southey, Melissa C. , Swerdlow, Anthony J. , Tham, Emma , Trovik, Jone , Turman, Constance , Tyrer, Jonathan P. , Vachon, Celine , VanDen Berg, David , Webb, Penelope M. , Wentzensen, Nicolas , Werner, Henrica M. J. , Winham, Stacey J. , Wolk, Alicja , Xia, Lucy , Xiang, Yong-Bing , Yu, Herbert , Zheng, Wei , Kraft, Peter , De Vivo, Immaculata , Tomlinson, Ian , Easton, Douglas F. , Spurdle, Amanda B. and Thompson, Deborah J.

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London: Nature Publishing Group UK

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Nature communications, 2018-08, Vol.9 (1), p.3166-12, Article 3166

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English

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London: Nature Publishing Group UK

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Endometrial cancer is the most commonly diagnosed cancer of the female reproductive tract in developed countries. Through genome-wide association studies (GWAS), we have previously identified eight risk loci for endometrial cancer. Here, we present an expanded meta-analysis of 12,906 endometrial cancer cases and 108,979 controls (including new geno...