Myonectin protects against skeletal muscle dysfunction in male mice through activation of AMPK/PGC1α...
Myonectin protects against skeletal muscle dysfunction in male mice through activation of AMPK/PGC1α pathway
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Author / Creator
Ozaki, Yuta , Ohashi, Koji , Otaka, Naoya , Kawanishi, Hiroshi , Takikawa, Tomonobu , Fang, Lixin , Takahara, Kunihiko , Tatsumi, Minako , Ishihama, Sohta , Takefuji, Mikito , Kato, Katsuhiro , Shimizu, Yuuki , Bando, Yasuko K. , Inoue, Aiko , Kuzuya, Masafumi , Miura, Shinji , Murohara, Toyoaki and Ouchi, Noriyuki
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
To maintain and restore skeletal muscle mass and function is essential for healthy aging. We have found that myonectin acts as a cardioprotective myokine. Here, we investigate the effect of myonectin on skeletal muscle atrophy in various male mouse models of muscle dysfunction. Disruption of myonectin exacerbates skeletal muscle atrophy in age-asso...
Alternative Titles
Full title
Myonectin protects against skeletal muscle dysfunction in male mice through activation of AMPK/PGC1α pathway
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c250c71bf72e4092a4450291dedd63dd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c250c71bf72e4092a4450291dedd63dd
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-40435-2
