Simultaneous Determination of Bufalin and Its Nine Metabolites in Rat Plasma for Characterization of...
Simultaneous Determination of Bufalin and Its Nine Metabolites in Rat Plasma for Characterization of Metabolic Profiles and Pharmacokinetic Study by LC–MS/MS
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Author / Creator
Wei, Wenlong , Yu, Yang , Wang, Xia , Yang, Linhui , Zhang, Hang , Ji, Hongjian , Li, Zhenwei , Hou, Jinjun , Wu, Wanying and Guo, Dean
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Characterization and determination of metabolites to monitor metabolic pathways play a paramount role in evaluating the efficacy and safety of medicines. However, the separation and quantification of metabolites are rather difficult due to their limited contents in vivo, especially in the case of Chinese medicine, due to its complexity. In this stu...
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Full title
Simultaneous Determination of Bufalin and Its Nine Metabolites in Rat Plasma for Characterization of Metabolic Profiles and Pharmacokinetic Study by LC–MS/MS
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TN_cdi_doaj_primary_oai_doaj_org_article_c25c31b684304a2e8c80b894a80970d5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c25c31b684304a2e8c80b894a80970d5
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules24091662