Anti-tau conformational scFv MC1 antibody efficiently reduces pathological tau species in adult JNPL...
Anti-tau conformational scFv MC1 antibody efficiently reduces pathological tau species in adult JNPL3 mice
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Tau, the main component of the neurofibrillary tangles (NFTs), is an attractive target for immunotherapy in Alzheimer's disease (AD) and other tauopathies. MC1/Alz50 are currently the only antibodies targeting a disease-specific conformational modification of tau. Passive immunization experiments using intra-peritoneal injections have previously sh...
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Anti-tau conformational scFv MC1 antibody efficiently reduces pathological tau species in adult JNPL3 mice
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TN_cdi_doaj_primary_oai_doaj_org_article_c2aa948c726941f2a8f9c5e6ab08b8ac
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c2aa948c726941f2a8f9c5e6ab08b8ac
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-018-0585-2
