Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology
Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The distinct spatial architecture of the apical actin cables (or actin cap) facilitates rapid biophysical signaling between extracellular mechanical stimuli and intracellular responses, including nuclear shaping, cytoskeletal remodeling, and the mechanotransduction of external forces into biochemical signals. These functions are abrogated in lamin...
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Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology
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TN_cdi_doaj_primary_oai_doaj_org_article_c2db46571a9e4e98b6c92809cc4d07ae
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c2db46571a9e4e98b6c92809cc4d07ae
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-02217-5