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Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology

Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c2db46571a9e4e98b6c92809cc4d07ae

Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology

About this item

Full title

Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-12, Vol.8 (1), p.2123-13, Article 2123

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The distinct spatial architecture of the apical actin cables (or actin cap) facilitates rapid biophysical signaling between extracellular mechanical stimuli and intracellular responses, including nuclear shaping, cytoskeletal remodeling, and the mechanotransduction of external forces into biochemical signals. These functions are abrogated in lamin...

Alternative Titles

Full title

Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c2db46571a9e4e98b6c92809cc4d07ae

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c2db46571a9e4e98b6c92809cc4d07ae

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-02217-5

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