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Increased NKX6.1 expression and decreased ARX expression in alpha cells accompany reduced beta-cell...

Increased NKX6.1 expression and decreased ARX expression in alpha cells accompany reduced beta-cell...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c300c6ee3216488eba26a29cf66434e5

Increased NKX6.1 expression and decreased ARX expression in alpha cells accompany reduced beta-cell volume in human subjects

About this item

Full title

Increased NKX6.1 expression and decreased ARX expression in alpha cells accompany reduced beta-cell volume in human subjects

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-09, Vol.11 (1), p.17796-17796, Article 17796

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Pancreatic islet cells have plasticity, such as the abilities to dedifferentiate and transdifferentiate. Islet cell conversion to other characteristic cell is largely determined by transcription factors, but significance of expression patterns of these transcription factors in human islet cells remained unclear. Here, we present the NKX6.1-positive...

Alternative Titles

Full title

Increased NKX6.1 expression and decreased ARX expression in alpha cells accompany reduced beta-cell volume in human subjects

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c300c6ee3216488eba26a29cf66434e5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c300c6ee3216488eba26a29cf66434e5

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-97235-1

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