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Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics

Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c334158e79f74f09bd8df84c3b7562c1

Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Clonal diversity is a consequence of cancer cell evolution driven by Darwinian selection. Precise characterization of clonal architecture is essential to understand the evolutionary history of tumor development and its association with treatment resistance. Here, using a single-cell DNA sequencing, we report the clonal architecture and mutational h...

Alternative Titles

Full title

Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c334158e79f74f09bd8df84c3b7562c1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c334158e79f74f09bd8df84c3b7562c1

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-19119-8

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