CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity
CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Natural killer (NK) cells are known to mediate killing of various cancer types, but tumor cells can develop resistance mechanisms to escape NK cell-mediated killing. Here, we use a “two cell type” whole genome CRISPR-Cas9 screening system to discover key regulators of tumor sensitivity and resistance to NK cell-mediated cytotoxicity in human gliobl...
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Full title
CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity
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TN_cdi_doaj_primary_oai_doaj_org_article_c3382b59f84941a4b245398b952b3433
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c3382b59f84941a4b245398b952b3433
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-29469-0
