Preventive action of benztropine on platinum-induced peripheral neuropathies and tumor growth
Preventive action of benztropine on platinum-induced peripheral neuropathies and tumor growth
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Contents
The endogenous cholinergic system plays a key role in neuronal cells, by suppressing neurite outgrowth and myelination and, in some cancer cells, favoring tumor growth. Platinum compounds are widely used as part of first line conventional cancer chemotherapy; their efficacy is however limited by peripheral neuropathy as a major side-effect. In a mu...
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Full title
Preventive action of benztropine on platinum-induced peripheral neuropathies and tumor growth
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TN_cdi_doaj_primary_oai_doaj_org_article_c3582322f54644c6b577dc223f566b32
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c3582322f54644c6b577dc223f566b32
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-019-0657-y
