Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Krabbe disease (KD) is a neurodegenerative disorder caused by the lack of β- galactosylceramidase enzymatic activity and by widespread accumulation of the cytotoxic galactosyl-sphingosine in neuronal, myelinating and endothelial cells. Despite the wide use of Twitcher mice as experimental model for KD, the ultrastructure of this model is partial an...
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Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
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TN_cdi_doaj_primary_oai_doaj_org_article_c37d72751ae0467d9065e594228807fd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c37d72751ae0467d9065e594228807fd
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-016-0001-8
