Log in to save to my catalogue

Structural basis of organic cation transporter-3 inhibition

Structural basis of organic cation transporter-3 inhibition

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c390514bb74345508edbb1e105eb04af

Structural basis of organic cation transporter-3 inhibition

About this item

Full title

Structural basis of organic cation transporter-3 inhibition

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-11, Vol.13 (1), p.6714-13, Article 6714

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Organic cation transporters (OCTs) facilitate the translocation of catecholamines, drugs and xenobiotics across the plasma membrane in various tissues throughout the human body. OCT3 plays a key role in low-affinity, high-capacity uptake of monoamines in most tissues including heart, brain and liver. Its deregulation plays a role in diseases. Despi...

Alternative Titles

Full title

Structural basis of organic cation transporter-3 inhibition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c390514bb74345508edbb1e105eb04af

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c390514bb74345508edbb1e105eb04af

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-34284-8

How to access this item