Safety evaluations of a synthetic antimicrobial peptide administered intravenously in rats and dogs
Safety evaluations of a synthetic antimicrobial peptide administered intravenously in rats and dogs
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The antimicrobial peptide SET-M33 is under study for the development of a new antibiotic against major Gram-negative pathogens. Here we report the toxicological evaluation of SET-M33 administered intravenously to rats and dogs. Dose range finding experiments determined the doses to use in toxicokinetic evaluation, clinical biochemistry analysis, ne...
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Full title
Safety evaluations of a synthetic antimicrobial peptide administered intravenously in rats and dogs
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TN_cdi_doaj_primary_oai_doaj_org_article_c39f73ebda9d4c7f855e7b355d6f43c5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c39f73ebda9d4c7f855e7b355d6f43c5
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-23841-2
